Endocrine Abstracts

Transsphenoidal surgery is the treatment of choice in acromegaly. However, some patients do not achieve postoperative remission. The aim of our study was to identify factors that predictive of a poor surgical outcome in patients with acromegaly. In our study we included 39 acromegalic patients, who underwent transsphenoidal surgery as initial treatment. We evaluated clinical, hormonal and radiological predictors based on magnetic resonance imaging (MRI). Also we examined immun...

The degree of hormonal activity and the duration of active phase of disease are the most important factors in the pathogenesis of system complications, decreasing life span in patients with acromegaly. To determine the age-related features of the clinical course of disease 140 patients with active acromegaly were examined. All patients were divided into 3 groups: group 1 included 14 patients at the age of 20–39, group 2 – 40–59 (72) and group 3 – ≥60 ...